Do Viruses Help?
HOW ABOUT VIRUSES? Just like bacteria viruses are one of the microbes that
are winning the match against the humans. Viruses were the toughest one to
tackle for the scientist. The shape, contents and their protective shields were
the most challenging part of the fight. There are many ways one can treat
cancer, but for AIDS doctors prescribe a cocktail of drugs in which some are
enzyme inhibitors, protein inhibitors and while some are RNA inhibitors. This is
not it in the cocktail there is more to the list. As the technology increases
and the knowledge of our scientist about the DNA, RNA, Viruses, Bacteria, and
other interesting things we are a step closer to the destruction of the virus.
The hardest part of the virus is that it mutates a lot. Just like bacteria
viruses do get resistant to drugs we take against them. For example if one
catches cold or flu the doctors prescribe Amoxicycilin or something similar to
it. If the patient doesn’t finish the dosage there is a likelihood for the cold
virus to get resistant to Amoxicycilin resulting a second drug intake.
Pharmaceutical industries are trying to take a new approach to make antiviral
drugs. One recently developed shows remarkable effects on the herpes virus. The
recent antiviral drug indirectly attacks the virus making it hard for the virus
to develop resistance to. Until today what the antiviral drugs did was they
interfered with the production of the essential protein by the viruses. Viruses
are also denoted as parasites, meaning that they infect a host as its life
support.
To fight the war against the viruses University of Pennsylvania Medical
Center researches took the herpes simplex virus for experimental purpose, they
found out that by inhibiting certain set of cellular enzymes they can
successfully stop all the viral activity which causes the host to become sick.
“These enzymes are called cyclin-dependent kinases, or cdks. This enzyme along
with other enzymes drive and coordinate cell division.” This enzyme is also used
by other viruses for replication purposes thus what Penn. team did was they too
the cdks inhibitor and infected the virus with it, the result that came out was
that the cells didn’t replicate and the host cells were healthy. According to
the statistics Herpes Simplex Virus 1 and Herpes Simplex Virus 2 strains have
infected 80% and 20% respectively, the remarkable thing is that these cdks
inhibitors work best on these two strains of HSV. Along with these two strains
of HSV there is a third strain called Human CytoMegloVirus or HCMV which infects
also 80% of the people, the cdks inhibitors shut this virus down for good. Tests
are going to be conducted on the HIV, adenovirus, papovavirus, and parvovirus
with the cdks inhibitors for these viruses work almost the same as HSV. If this
drug works there might be a possibility for the people who have one of these
viruses to be cured with one pill or with a cocktail in which one more pill is
added to it. But the fight against viruses is not easy to win for they are just
more complicated than what we think it is. I learned that human race has still
one more chance to survive for few more years. Before I read this article I
thought that just like dinosaurs were extinct we are going to be too. But the
only difference will be that they didn’t know their reason of what caused the
wiping of their race but we will Viruses.
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